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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP14
All Species:
26.06
Human Site:
T299
Identified Species:
38.22
UniProt:
P54578
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54578
NP_001032411.1
494
56069
T299
L
R
L
Q
E
E
I
T
K
Q
S
P
T
L
Q
Chimpanzee
Pan troglodytes
P60051
493
55922
T299
L
R
L
Q
E
E
I
T
K
Q
S
P
T
L
Q
Rhesus Macaque
Macaca mulatta
XP_001090667
458
52239
Q271
T
K
Q
S
P
T
L
Q
R
N
A
L
Y
I
K
Dog
Lupus familis
XP_537306
545
61461
T350
L
R
L
Q
E
E
I
T
K
Q
S
P
T
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMA1
493
55983
T299
L
R
L
Q
E
E
I
T
K
Q
S
P
T
L
Q
Rat
Rattus norvegicus
NP_001008302
493
55958
T299
L
R
L
Q
E
E
I
T
K
Q
S
P
T
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519267
431
48760
R244
K
Q
S
P
T
L
Q
R
N
A
L
Y
I
K
S
Chicken
Gallus gallus
XP_419150
492
55612
T297
L
R
L
Q
E
E
I
T
K
L
S
P
T
L
Q
Frog
Xenopus laevis
Q6GNI6
523
60030
I295
P
N
H
C
N
C
I
I
D
Q
I
F
T
G
G
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
D303
H
G
V
S
T
T
I
D
P
F
W
D
I
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609377
475
53689
V286
S
K
M
K
E
Q
L
V
K
K
S
E
T
L
G
Honey Bee
Apis mellifera
XP_395043
497
56311
T294
N
K
M
Q
E
Q
I
T
K
M
S
P
T
L
G
Nematode Worm
Caenorhab. elegans
Q17361
489
55859
N276
T
R
N
S
E
E
L
N
R
D
A
K
W
Q
K
Sea Urchin
Strong. purpuratus
XP_786966
516
58357
V300
N
R
L
Q
E
S
L
V
K
S
S
P
T
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q949Y0
482
53677
E279
H
G
L
K
G
E
L
E
K
T
S
P
A
L
G
Baker's Yeast
Sacchar. cerevisiae
P43593
499
57092
E285
E
G
L
N
E
K
I
E
K
R
S
D
L
T
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
92.5
89.9
N.A.
96.7
96.5
N.A.
80.3
90.4
21.4
20.1
N.A.
54.6
61.7
41.9
61
Protein Similarity:
100
99.8
92.7
90.2
N.A.
98.5
98.7
N.A.
83.8
94.9
39
38.7
N.A.
71.2
80.2
61.1
76.5
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
0
93.3
20
6.6
N.A.
33.3
60
20
60
P-Site Similarity:
100
100
40
100
N.A.
100
100
N.A.
6.6
93.3
20
13.3
N.A.
73.3
80
46.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.5
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.9
46.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
7
13
0
7
0
0
% A
% Cys:
0
0
0
7
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
7
7
7
0
13
0
0
0
% D
% Glu:
7
0
0
0
69
50
0
13
0
0
0
7
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% F
% Gly:
0
19
0
0
7
0
0
0
0
0
0
0
0
7
32
% G
% His:
13
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
63
7
0
0
7
0
13
7
0
% I
% Lys:
7
19
0
13
0
7
0
0
69
7
0
7
0
7
13
% K
% Leu:
38
0
57
0
0
7
32
0
0
7
7
7
7
63
7
% L
% Met:
0
0
13
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
13
7
7
7
7
0
0
7
7
7
0
0
0
0
7
% N
% Pro:
7
0
0
7
7
0
0
0
7
0
0
57
0
0
0
% P
% Gln:
0
7
7
50
0
13
7
7
0
38
0
0
0
7
38
% Q
% Arg:
0
50
0
0
0
0
0
7
13
7
0
0
0
0
0
% R
% Ser:
7
0
7
19
0
7
0
0
0
7
69
0
0
7
7
% S
% Thr:
13
0
0
0
13
13
0
44
0
7
0
0
63
7
0
% T
% Val:
0
0
7
0
0
0
0
13
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _